David A. Sinclair

Harvard Professor and Aging Researcher—Co-founder of Multiple Biotech Companies Pioneering Longevity Science

Aging BiologyEpigenetics and Epigenetic ReprogrammingSirtuins and NAD+ BiologyLongevity Genes and InterventionsMitochondrial Function and MetabolismNeurodegeneration and Nerve Regeneration
Connect
Explore

About David A. Sinclair

David A. Sinclair - Biography

David A. Sinclair is an Australian-American biologist and tenured professor at Harvard Medical School, renowned for his research on aging and epigenetics. He has co-founded multiple biotechnology companies focused on aging and age-related diseases.

David Andrew Sinclair was born on June 26, 1969, in Australia. He earned a Bachelor of Science degree in biochemistry and a Ph.D. in molecular genetics from the University of New South Wales. Following his doctoral work, Sinclair completed postdoctoral training at MIT under Leonard P. Guarente. In 1999, Sinclair was hired by Harvard Medical School, where he established his own laboratory focused on longevity genes and aging biology. Sinclair has co-founded numerous biotechnology companies advancing aging research and translational medicine. He authored the bestselling book 'Lifespan: Why We Age—and Why We Don't Have To', which became influential in the longevity field.

Learn from David when you're...

  • Pursuing strategies to slow or reverse biological aging processes
  • Exploring epigenetic reprogramming to restore youthful cellular function
  • Addressing age-related decline in mitochondrial function or energy metabolism
  • Implementing longevity interventions like NAD+ boosters
  • Tackling neurodegeneration challenges
  • Developing treatments for common age-related diseases
  • Innovating in biotech for healthspan extension
  • Optimizing personal health practices amid modern comforts
Mentor framework guide

What can you ask about David A. Sinclair's work?

In Get Mentors, you can explore a knowledgeable guide grounded in David A. Sinclair's public ideas and frameworks, then turn the conversation into daily actions with Mentor Board, Goal Sprints, Roundtable, and Coaching Mode.

Best for these goals

  • Aging Biology
  • Epigenetics And Epigenetic Reprogramming
  • Sirtuins And NAD+ Biology
  • Longevity Genes And Interventions

Core frameworks

  • Embrace aging as a treatable disease rather than an inevitable fate
  • Practice intermittent fasting or eat less often to activate survival genes
  • Consume mostly stressed plants and minimize animal proteins to signal longevity pathways
  • Aging Biology

Sample questions

  • Which David framework applies to my current goal?
  • What would David's public work suggest I consider?
  • How can I turn this David idea into a concrete action?
  • What blind spot would this mentor framework help me notice?

Example query: ask about David's public frameworks, pressure-test your decision, or compare that lens with another mentor framework in Roundtable.

Ready to Learn from David A. Sinclair?

Download the Get Mentors app and explore mentor frameworks with guided daily actions.

Download the App